Introduction Impairments in decision-making processes are believed to play an important role in both substance use disorders and behavioral addictions.Clinical and pre-clinical experimental testing provide complimentary insights on the psychobiological mechanisms of decision-making.The IOWA Gambling Task (IGT) assesses decision-making under ambigui
Image reconstruction of fluorescent molecular tomography based on the tree structured Schur complement decomposition
Abstract Background The inverse problem of fluorescent molecular tomography (FMT) often involves complex large-scale matrix operations, which may lead to unacceptable computational errors and complexity.In this research, a tree structured Schur complement decomposition strategy is proposed to accelerate the reconstruction process and reduce the com
Differential Susceptibility and Innate Immune Response of Aedes aegypti and Aedes albopictus to the Haitian Strain of the Mayaro Virus
Mayaro (MAYV) is an emerging arthropod-borne virus belonging to the Alphavirus genus of the Togaviridae family.Although forest-dwelling Haemagogus mosquitoes have been Dice considered as its main vector, the virus has also been detected in circulating Aedes ssp mosquitoes.Here we assess the susceptibility of Aedes aegypti and Aedes albopictus to in
Posttranslational modification by an isolevuglandin diminishes activity of the mitochondrial cytochrome P450 27A1[S]
Posttranslational modification by isolevuglandins (isoLGs), Wash and Lotion arachidonate oxidation products, is an important yet understudied process associated with altered protein properties.This type of modification is detected in cytochrome P450 27A1 (CYP27A1), a multifunction enzyme expressed in almost every cell and involved in the metabolism